The opioid system in cardiac and vascular regulation of normal and hypertensive states.

Effect of apelin on cardiac contractility in acute reno-vascular hypertension: The role of apelin receptor and kappa opioid receptor heterodimerization

Objective(s): Apelin/APJ system plays an important role in the regulation of myocardial contractility (MC) and blood pressure. Opioid receptors (OPRs) are also important cardiovascular regulators and exert many of their effects through modulating the function of other systems. This study analyzed the interaction between APJ and kappa OPRs (KOR) in cardiac responsiveness to apelin in acute reno-...

Inter-Operative Time between Neurosurgery and Cardiac Surgery for Native Valve Endocarditis

Introduction: Infective endocarditis is well known to produce neurologic complications from septic emboli, which mandates a multidisciplinary approach between neurosurgery and cardiac surgery. However, literature is not clear as to the optimal interval length between neurosurgery and cardiac surgery.Presentation of Cases: The first case involves a 60-year-old woman with significant past medical...

Investigation of the Changes in Serum Intercellular and Vascular Adhesion Molecules (ICAM-1 and VCAM-1) and Nitric Oxide Levels in Response to Exercise Training and L-arginine Supplementation in Postmenopausal Hypertensive Women

Evaluation of Cardiac Function in Patients with Brain Death using Advanced Hemodynamic Monitoring

Background: Studies on hemodynamic changes in brain death are in vitro and in animal studies. And very few studies have been done on the hemodynamic changes of brain death. The aim of this study was to use advanced hemodynamic monitoring with echocardiography for evaluation of donated heart and to evaluate the moment by moment brain death patients with advanced hemodynamic monitoring tools and ...

Self-Regulation Behaviors of Hypertension and Related Factors Among Hypertensive Patients

Background & Objectives: Hypertension is the most important cause of all cardiovascular diseases, stroke, heart attack, renal disease, which is usually incurable. Management of the disease requires a certain degree of self-regulation. The aim of this study was to investigate the self-regulation behaviors of hypertension and related factors among hypertensive patients. Material & Methods: This C...